ISSN 1006-298X      CN 32-1425/R

导航

肾脏病与透析肾移植杂志 ›› 2015, Vol. 24 ›› Issue (2): 176-180.

• 论文 • 上一篇    下一篇

糖尿病肾病调脂治疗的临床应用

  

  • 出版日期:2015-04-28 发布日期:2015-04-29

Lipid Lowering Agents in Diabetic Nephropathy

  • Online:2015-04-28 Published:2015-04-29

摘要:

摘要:糖尿病肾病患者发生心血管事件的风险显著升高,与脂代谢紊乱密切相关。导致脂代谢紊乱的原因复杂多样,长期高血糖诱导血管内皮损伤进一步增加胆固醇(TG)水平、降低高密度胆固醇(HDL-c)水平。因此,调脂药物被临床广泛应用于糖尿病肾脏的治疗。本文就调脂药物在糖尿病肾病的临床应用及研究新进展做一综述。

关键词: 糖尿病肾病, 血脂异常, 心血管事件, 调脂脂药

Abstract:

Abstract: It is well known that patients with diabetic nephropathy have a high incidence of cardiovascular disease (CVD). The mechanisms for dyslipidemia in diabetic nephropathy are multifactorial and complex. Long-term hyperglycemia causes generalized vascular endothelial damage, leading to increased triglyceride (TG) levels and decreased high-density lipoprotein cholesterol (HDL-c). The implications of lipid lowering drugs in the treatment of diabetic nephropathy have been considered. The review focuses on the clinical efficacy and safety of lipid lowering drugs in the treatment of diabetic nephropathy.

Key words: diabetic nephropathy, dyslipidemia, cardiovascular Disease , lipid lowering drugs