肾脏病与透析肾移植杂志
• 论文 • 上一篇 下一篇
出版日期:
发布日期:
Online:
Published:
摘要： 糖尿病肾病是糖尿病最常见的严重并发症，也是慢性肾脏病进展到终末期肾脏病的主要病因之一。糖尿病肾病早期表现为肾小球内高压力、高灌注和高滤过，随后出现微量白蛋白尿、显性蛋白尿、肾小球滤过率降低，最终可发展为终末期肾病。近年来，糖尿病患者蛋白尿的发生率有所下降，但肾小球滤过率减低的发生率上升，提示非蛋白尿型糖尿病肾病的发病率升高，引起多种血管并发症和肾功能降退。因此，了解非蛋白尿型糖尿病肾病的发病机制，诊断标志物和治疗措施，是有效治疗糖尿病肾病改善疾病预后的基础。
关键词: 糖尿病肾病, 非蛋白尿型糖尿病肾病, 肾血管并发症
Abstract: As the major complication of diabetes,diabetic nephropathy is also the major cause of progression from chronic kidney disease to end stage renal disease.However,the incidence of nonproteinuria diabetic nephropathy（NPDN）in patients with type 2 diabetes is gradually increasing,causing vascular complications and renal function decrease.Therefore,understanding the pathogenesis,diagnostic markers and therapies of NPDN is the basis of effective treatment of diabetic nephropathy.
马妍,谢红浪. 非蛋白尿型糖尿病肾病[J]. 肾脏病与透析肾移植杂志, DOI: 10.3969/j.issn.1006-298X.2020.04.015.
MA Yan,XIE Honglang. Non-proteinuria diabetic nephropathy[J]. Chinese Journal of Nephrology, Dialysis & Transplantation, DOI: 10.3969/j.issn.1006-298X.2020.04.015.
0 / / 推荐
导出引用管理器 EndNote|Ris|BibTeX
链接本文: http://www.njcndt.com/CN/10.3969/j.issn.1006-298X.2020.04.015
http://www.njcndt.com/CN/Y2020/V29/I4/369
