ISSN 1006-298X      CN 32-1425/R

导航

肾脏病与透析肾移植杂志 ›› 2023, Vol. 32 ›› Issue (3): 226-230.DOI: 10.3969/j.issn.1006-298X.2023.03.005

• • 上一篇    下一篇

人工血管保护外鞘预防移植肾动脉扭折的疗效

ZHOU Zheng, HUI Yu, HU Linkun, et al   

  • 出版日期:2023-06-28 发布日期:2023-07-01

Efficacy of artificial protective external vascular sheath in preventing graft artery kinking

  • Online:2023-06-28 Published:2023-07-01

摘要: 的:探讨同种异体肾移植手术中,采用膨胀泡沫聚四氟乙烯(ePTFE)人工血管包裹动脉预防移植肾动脉扭折的疗效及安全性。
方法:2019年1月至2022年6月苏州大学附属第一医院泌尿外科共行肾移植286例,其中8例移植肾摆放于髂窝后出现动脉扭折,存在影响移植肾血供风险,术中遂采用ePTFE人工血管作为外鞘包裹移植肾动脉。本文回顾性分析了这些患者术前、术中及术后临床资料,评估该方法的疗效及安全性。
结果:8例患者中男性6例、女性2例,平均年龄43.1±8.5岁。所有患者均采用右侧供肾动脉与受者髂内动脉端端吻合,并放置于右侧髂窝,供肾均为单支动脉。移植肾放置于右髂窝后,动脉扭折明显,其中2例术中出现移植肾张力减弱,色泽变暗,余6例术中未发现色泽张力变差。8例患者术中均采用ePTFE人工血管作为外鞘包裹移植肾动脉后放置髂窝,移植肾色泽张力始终良好。术后第1天移植肾超声示主肾动脉平均流速为146.7±10.4 cm/s,平均阻力指数为0.68±0.06。8例患者中1例出现移植肾功能延迟恢复(DGF),术后第5天尿量逐渐增多,2周时肾功能恢复正常,其余患者均恢复顺利。所有患者均未出现急性排斥反应、移植肾动脉血栓或感染等,移植肾超声造影和MR评估移植肾血管走行未见异常。术后第3月超声下平均主肾动脉流速及阻力指数分别为151.3±7.8 cm/s和0.67±0.07,与术后第1天超声结果无统计学差异(P>0.05)。随访至2023年1月,8例患者移植肾均存活,无移植肾动脉狭窄、感染及移植肾区不适等。
结论:肾移植手术中遇到动脉扭折影响移植肾血供时,ePTFE人工血管保护外鞘可有效纠正血管走行,改善移植肾血供,减少移植肾动脉狭窄可能,具有操作简单、安全性高、并发症少等优势。


关键词: 肾移植, 移植肾动脉扭折人, 工血管

Abstract: Objective:To investigate the curative effect and safety of artificial expanded polytetrafluorethylene (ePTFE) protective external vascular sheath for kinked transplanted renal artery.
Methodology:A total of 286 kidney transplants were performed between January 2019 and June 2022 at the First Affiliated Hospital of Soochow University, of which 8 cases presented with excessive anastomotic artery length and arterial kinking after placement in the iliac fossa, affecting the blood supply of transplanted kidney. An artificial ePTFE external vascular sheath was then used to wrap and immobilize the anastomotic artery during the operation. Demographics, preoperative, and postoperative recovery data of those patients were retrospectively analyzed, and the efficacy and safety of the method were evaluated.
Results:Among the 8 patients, 6 were male and 2 were female, with an average age of 43.1±8.5 years. All 8 cases had a kinked anastomotic artery when the right donor kidney with a single branch artery was anastomosed end-to-end with the recipient internal iliac artery. Two cases exhibited a weakened pulsation of transplant kidney and a darkening of its color immediately after the kidney was placed in the right iliac fossa. No deterioration of color or tension was found in the remaining 6 cases. The application of an artificial ePTFE external vascular sheath significantly corrected the kinked artery and improved blood supply of the transplanted kidney. Postoperative ultrasonography showed that the arterial velocity was 146.7±10.4 cm/s, and the resistance index (RI) was 0.68±0.06. All of the patients recovered normally after surgery except for one case that developed delayed graft function (DGF), with a gradual increase in urine output on the fifth postoperative day and a return to normal renal function in the second week. No rejection, arterial thrombosis, or infection occurred, and no abnormalities were observed under the ultrasound or CT. The flow velocity and RI in the third month after the operation were 151.3±7.8 cm/s and 0.67±0.07, respectively. There were no significant differences compared to the immediate postoperative data (P>005). All 8 cases survived without any manifestations of renal artery stenosis, infection and discomfort in the surgical area.
Conclusion:The ePTFE protective external sheath effectively corrected the kinked anastomotic artery, improved the blood supply, and reduced the possibility of longterm stenosis in the transplanted renal artery. It demonstrated good stability, high safety and few complications.


Key words: renal transplantation, renal artery kinking, vascular graft