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肾脏病与透析肾移植杂志 ›› 2026, Vol. 35 ›› Issue (1): 34-38.DOI: 10.3969/j.issn.1006⁃298X.2026.01.006

• 论著 • 上一篇    下一篇

自体动静脉内瘘支架穿刺行血液透析的安全性与疗效

  

  • 出版日期:2026-02-27 发布日期:2026-02-27

Safety and efficacy of stent puncture in autologous arteriovenous fistulas for hemodialysis patients

  • Online:2026-02-27 Published:2026-02-27

摘要: 目的:探讨血液透析患者自体动静脉内瘘 (AVF) 支架穿刺透析的可行性和有效性,为临床实践提供参考依据。 方法:回顾性纳入 2022 年 11 月至 2025 年 9 月在浙江大学医学院附属邵逸夫医院因 AVF 穿刺区域复发性狭窄植入支架,并在 AVF 支架穿刺透析的 16 例患者。收集患者临床资料及术后相关随访资料,统计其技术成功率、临床成功率及 6 个月、12 个月的通畅率。 结果:共纳入 16 例 AVF 狭窄支架置入患者,包括 ELUVIA 药物洗脱支架 (12 个,11 例患者) 与金属裸支架 (镍钛合金支架)(5 个,5 例患者)。支架植入技术成功率 100%, 支架首次穿刺成功率 100%。支架植入术后 6 个月的靶病变初级通畅率 100%;12 个月内发生再狭窄 3 例,靶病变初级通畅率为 63.5%。6 个月和 12 个月的全通路初级通畅率分别为 92.3% 和 65.9%, 全通路次级通畅率均为 100%。ELUVIA 药物洗脱支架与金属裸支架 (镍钛合金支架) 在 6 个月靶病变初级通畅率均为 100%,12 个月分别为 83.3% 和 0%。支架穿刺平均随访 302d, 未出现支架断裂和感染等并发症。 结论:在 AVF 穿刺区域植入支架并用于穿刺具有较高的安全性,早期和中期通畅率良好,具有临床应用的可行性。

关键词: 血液透析, 血管通路, 支架穿刺, 自体动静脉内瘘, 狭窄

Abstract: Objective:To explore the feasibility and effectiveness of puncture of arteriovenous fistula (AVF) stents in hemodialysis patients, providing a reference for clinical practice. Methods:A retrospective analysis was conducted on 16 patients who underwent stent placement for recurrent stenosis in the puncture area of AVF at Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, between November 2022 and September 2025, and subsequently used these stents for dialysis needle cannulation. Patient clinical data and postoperative follow⁃up information were collected. Calculate its technical success rate, clinical success rate, and the patency rates at 6 months and 12 months. Results:A total of 16 patients with AVF stenosis underwent stent implantation, including ELUVIA drug⁃eluting stents (12 stents in 11 patients) and bare⁃metal stents (nitinol stents) (5 stents in 5 patients). The technical success rate of stent implantation was 100%, and the success rate of initial stent puncture for dialysis was 100%. The primary target lesion patency rate at 6 months post⁃stent implantation was 100%. Within 12 months, restenosis occurred in 3 cases, resulting in a primary target lesion patency rate of 63.5%. The primary circuit patency rates at 6 and 12 months were 92.3% and 65.9%, respectively, while the secondary circuit patency rates were both 100%. The ELUVIA drug⁃eluting stent and the bare⁃metal stent (nitinol stent) both demonstrated a 100% primary patency rate of the target lesion at 6 months, with rates of 83.3% and 0% respectively at 12 months. During a mean follow⁃up of 302 days for stent cannulation, no complications such as stent fracture or infection were observed. Conclusion:Stent placement in the puncture area of AVF for hemodialysis needle cannulation demonstrates a high safety profile and favorable early and mid⁃term patency rates, indicating its feasibility for clinical application.

Key words: hemodialysis, vascular access, stent puncture, arteriovenous fistula, stenosis