ISSN 1006-298X      CN 32-1425/R

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肾脏病与透析肾移植杂志 ›› 2025, Vol. 34 ›› Issue (4): 354-358.DOI: 10.3969/j.issn.1006-298X.2025.04.011

• 医学继续教育 • 上一篇    下一篇

血液透析血管通路相关胸廓出口综合征诊治进展

  

  • 出版日期:2025-08-28 发布日期:2025-08-28

Advances on the diagnosis and treatment of hemodialysis vascular access-associated thoracic outlet syndrome

  • Online:2025-08-28 Published:2025-08-28

摘要: 血液透析血管通路相关胸廓出口综合征(VA-TOS)是血液透析患者的少见并发症,其发病与锁骨下静脉胸廓出口处本身存在解剖狭窄、内瘘建立后高血流量刺激内膜增生及中心静脉置管损伤相关。典型表现包括通路侧肢体肿胀、疼痛、皮肤发绀、上肢浅静脉曲张及通路功能不良。诊断主要依赖于超声、计算机断层扫描血管造影、数字减影血管造影等影像学检查。治疗方案包括腔内介入、减压手术、经皮肋锁关节血管外旁路术、血液透析可靠流出道移植物、锁骨下静脉旁路手术和限流手术等,需根据患者的全身状况及病情严重程度进行个体化选择。本文就 VA-TOS 的发生机制、临床表现、诊断及治疗的相关进展作一综述。

关键词: font-family:Inter, -apple-system, BlinkMacSystemFont, ", font-size:16px, background-color:#F9FAFB, ">血液透析, 血管通路相关胸廓出口综合征, 腔内介入治疗, 减压手术, 血管旁路术

Abstract: Vascular access-related thoracic outlet syndrome (VA-TOS) is a rare complication in hemodialysis patients, which is closely associated with anatomical stenosis of the subclavian vein at the thoracic outlet, endothelial hyperplasia stimulated by the high blood flow of fistulas and central venous injury due to indwelling catheters. VA-TOS typically presents with progressive swelling and pain, cyanosis of the skin, upper limb superficial vein varicosity and dialysis dysfunction. The diagnosis mainly depends on imaging techniques such as ultrasound, computed tomography angiography, and digital subtraction angiography. Therapeutic strategies include endovascular interventions, surgical decompression, percutaneous costoclavicular bypass, hemodialysis reliable outflow graft, subclavian bypass, and flow reduction. This review summarizes the pathogenesis, clinical manifestations, diagnosis, and treatment of VA-TOS in hemodialysis patients.

Key words: font-family:Inter, -apple-system, BlinkMacSystemFont, ", font-size:16px, background-color:#F9FAFB, ">hemodialysis, vascular access-related thoracic outlet syndrome, endovascular interventions, surgical decompression, vascular bypass