Abstract:

Mitochondria are highly dynamic organelle undergoing continuous fusion and fission. Dysregulation of mitochondrial dynamics participates in the mechanism of neurodegenerative diseases, cardiac diseases and metabolic diseases. Recent studies found that mitochondrial dynamics disequilibrium participates in the mechanism of kidney disease and injury of tubular cell and podocyte. The progress on mitochondrial dynamics and kidney diseases is reviewed here in order to explore new agents for kidney protection.

Key words: mitochondrial dynamics, kidney injury, mechanism