ISSN 1006-298X      CN 32-1425/R

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肾脏病与透析肾移植杂志 ›› 2015, Vol. 24 ›› Issue (1): 85-89.

• 论文 • 上一篇    下一篇

远程缺血预处理对移植肾缺血再灌注损伤的保护作用

  

  • 出版日期:2015-02-28 发布日期:2015-03-07

Advances of remote ischemic preconditioning on Renal transplatation

  • Online:2015-02-28 Published:2015-03-07

摘要:

摘要] 移植肾缺血再灌注损伤(ischemic reperfusion injury,IRI) 是一个不可避免的过程,不仅影响移植肾功能早期恢复,还可影响移植肾长期功能和生存率。至今尚缺乏有效措施减少缺血/再灌注引起的损伤。远程缺血预处理可通过机体内源性保护机制提高肾脏对缺血/再灌注损伤的抵抗力,有望成为防治缺血再灌注损伤的新策略。

关键词: 缺血再灌注损伤, 肾移植, 远程缺血预处理

Abstract:

ABSTRACT kidney allograft ischemia-reperfusion injury (ischemic reperfusion injury, IRI) is an inevitable process, not only affects early graft function recovery, but also affects long-term graft function and survival. Up to now, there is still a lack of effective prevention and treatment strategies for reducing ischemia/reperfusion injury. Remote ischemic preconditioning can improve resistance of renal ischemia / reperfusion injury by endogenous protective mechanisms. It is expected to become the novel treatment strategies.

Key words: ischemic reperfusion injury, renal transplatation, remote ischemic preconditioning