ISSN 1006-298X      CN 32-1425/R

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肾脏病与透析肾移植杂志 ›› 2015, Vol. 24 ›› Issue (1): 80-84.

• 论文 • 上一篇    下一篇

腹膜透析患者的心血管钙化

  

  • 出版日期:2015-02-28 发布日期:2015-03-07

cardiovascular calcification and valvular calcification in peritoneal dialysis patients

  • Online:2015-02-28 Published:2015-03-07

摘要:

摘 要 超过80%的腹膜透析患者合并有心血管钙化,其中瓣膜钙化的的发生率在1/3以上,心血管及瓣膜钙化是心血管死亡及全因死亡的预测因素。年龄,透析龄,既往心血管疾病史,吸烟,炎症,高血压,糖尿病,血脂异常,高磷、高钙血症,甲状旁腺激素异常是其主要的危险因素。调整矿物质代谢异常以预防和治疗心血管及瓣膜钙化。本文就心血管及瓣膜钙化的流行病学、发病机制、相关因素、预后及治疗进行综述。

关键词: 腹膜透析, 心血管钙化, 瓣膜钙化

Abstract:

ABSTRACT  More than 80% of peritoneal dialysis patients are complicated with cardiovascular calcification, and more than one third have heart valve calcification. Calcification is a predictor of cardiovascular mortality and all-cause mortality. The main risk factors of calcification included age, dialysis vintage, previous cardiovascular disease, smoking, inflammation, hypertension, diabetes mellitus, dyslipidemia, hypercalcemia, hyperphospheremia, and abnormal parathyroid hormone. Adjusting mineral metabolism was used mainly to prevent and treat calcification. The prevalence of calcification, calcification mechanism, related factors, prognosis and treatment will be reviewed in this article.

Key words: peritoneal dialysis, cardiovascular calcification, valvular calcification