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肾脏病与透析肾移植杂志 ›› 2024, Vol. 33 ›› Issue (3): 226-232.DOI: 10.3969/j.issn.1006-298X.2024.03.005

• 论著 • 上一篇    下一篇

选择性神经阻滞在自体动静脉内瘘成形术中的应用及对内瘘成熟的影响

  

  • 出版日期:2024-06-28 发布日期:2024-06-26

Selective nerve block in the creation of arteriovenous fistulas and its effect on arteriovenous fistula maturation

  • Online:2024-06-28 Published:2024-06-26

摘要: 目的:评估选择性神经阻滞在自体动静脉内瘘(AVF)成形术中的有效性及对术后内瘘成熟率的影响。
方法:本研究为回顾性队列研究,选取2022-01-01~2022-12-31在北京大学第三医院海淀院区行AVF成形术的患者,根据术前麻醉类型分为选择性神经阻滞组(S组)和局部浸润麻醉组(L组)。采用视觉模拟评分法(VAS)比较两组患者术中的疼痛程度,术后即刻、4周、8周、12周的吻合血管内径及肱动脉血流量,并比较两组的内瘘成熟率。
结果:共纳入207例患者,S组44例(21.26%),L组163例(78.74%)。与L组相比,S组患者术前吻合血管内径更细(P<0.05),术中VAS更低(Z=-2.598,P=0.009),麻醉后5 min的吻合静脉内径、术后即刻肱动脉血流量更大(P<0.05)。S组患者术后内瘘头静脉内径及肱动脉血流量明显高于L组(均P<0.05),4周和8周时S组的成熟率明显高于L组(P均<0.05),12周时两组成熟率差异无统计学意义(χ2=1.616,P=0.204)。
结论:选择性神经阻滞用于AVF成形术时,可安全有效镇痛,兼具扩张血管、增加术后内瘘血流量及提高短期内瘘成熟率的优势,尤其适合于血管较细的患者。


关键词: 自体动静脉内瘘, 血液透析, 麻醉, 选择性神经阻滞, 局部浸润麻醉

Abstract: Objective:To evaluate the efficacy of selective nerve block in the creation of arteriovenous fistulas and its effect on arteriovenous fistula maturation.
Methodology:A retrospective cohort study. Patients who underwent arteriovenous fistula anastomosis in Haidian Hospital,the Third Hospital of Peking University from January 1 to December 31,2022 were divided into selective nerve block group and local infiltration anesthesia group according to the type of anesthesia before operation.The visual analogue pain score (VAS),the diameter of anastomotic vessels and the blood flow of brachial artery at immediately,4 weeks,8 weeks and 12 weeks after operation were compared between the two groups,and the fistula maturation was compared between the two groups.
Results:A total of 207 patients were included,including 44(21.26%) patients in selective nerve block group and 163(78.74%) patients in local infiltration anesthesia group. Compared with the local infiltration anesthesia group,the selective nerve block group had smaller preoperative anastomotic diameter(P<0.05),lower intraoperative VAS score(Z=-2.598,P=0.009),larger anastomotic vein diameter and brachial artery blood flow at 5 minutes after anesthesia(P<0.05). The internal diameter of cephalic vein and brachial artery blood flow of internal fistula in selective nerve block group were significantly higher than those in local infiltration anesthesia group (P<0.05). At 4 and 8 weeks,the fistula maturation in selective nerve block group was significantly higher than that in local infiltration anesthesia group (P<0.05). There was no significant difference between the two groups for AVF maturation at 12 weeks (X2=1.616,P=0.204).
Conclusion:Selective nerve block can provide safe and effective analgesia for AVF anastomosis,and has the advantages of increasing vascular diameter,postoperative internal fistula blood flow and improving short-term fistula maturation. It is a suitable anesthetic method for AVF anastomosis,especially for patients with smaller vascular diameter.


Key words: arteriovenous fistula, hemodialysis, anesthesia, selective nerve block, local infiltration anesthesia