ISSN 1006-298X      CN 32-1425/R

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肾脏病与透析肾移植杂志 ›› 2019, Vol. 28 ›› Issue (3): 277-281.DOI: 10.3969/j.issn.1006-298X.2019.03.017

• 论文 • 上一篇    下一篇

血清降钙素原在肾脏疾病患者合并感染的诊断价值

  

  • 出版日期:2019-06-28 发布日期:2019-07-23

Diagnostic value of serum procalcitonin in kidney disease complicated with infection

  • Online:2019-06-28 Published:2019-07-23

摘要:

血清降钙素原(PCT)在临床中已经得到广泛的应用,包括对细菌感染的鉴别诊断、病情严重程度的评价、临床抗生素治疗的监测等。肾脏作为维持机体内部环境相对稳定的重要器官,在PCT的清除代谢中发挥重要作用。肾功能的改变可影响PCT的水平,并且临床治疗手段如连续性肾脏替代治疗(CRRT)也会对血清PCT的临床应用价值产生影响。本文就血清PCT在泌尿系统感染、急性肾损伤、慢性肾脏病和CRRT等的临床应用价值进行综述。

关键词: 降钙素原, 肾脏疾病, 感染, 诊断

Abstract:

Serum procalcitonin (PCT) has been widely used in clinical practice,including the differential diagnosis of bacterial infection,the severity of disease,and the monitoring of clinical antibiotic treatment.As an important organ that maintains a relatively stable homeostasis,the kidney plays an important role in the clearance and metabolism of PCT.Changes in renal function may affect the level of PCT,and clinical treatments such as continuous renal replacement therapy (CRRT) can also has an impact on the clinical value of serum PCT.Here we  reviewed the clinical application value of serum PCT in urinary tract infection,acute and chronic renal insufficiency and CRRT.