ISSN 1006-298X      CN 32-1425/R

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肾脏病与透析肾移植杂志 ›› 2019, Vol. 28 ›› Issue (1): 73-77.DOI: 10.3969/j.issn.1006-298X.2019.01.016

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IgG4相关性肾病的病理改变及特征

  

  • 出版日期:2019-02-28 发布日期:2019-03-04

Pathological patterns and characteristics of IgG4related kidney disease

  • Online:2019-02-28 Published:2019-03-04

摘要:

IgG4相关疾病的肾脏受累统称为IgG4相关性肾病,是一种免疫介导的炎性纤维化疾病,可表现为间质性肾炎、肾小球性病变、腹膜后纤维化、肾脏炎性假瘤、慢性硬化性肾盂炎、肾动脉炎,其中以IgG4相关间质性肾炎最为常见,其次为IgG4相关膜性肾病,本文重点描述IgG4相关性肾病的病理改变及特征。

关键词: IgG4相关性肾病, 小管间质性肾炎, 膜性肾病, 肾脏病理

Abstract:

IgG4related kidney disease which is an immunemediated inflammatory fibrosis disease refers to all the kidney involvements of IgG4related disease.It can be presented as tubulointerstitial nephritis,glomerular disease,retroperitoneal fibrosis,renal inflammatory pseudotumor,chronic sclerosis pyelitis,and renal arteritis.IgG4related kidney disease has been found to most commonly manifest as IgG4related tubulointerstitial nephritis,followed by IgG4related membranous nephropathy.This article focuses on the pathological patterns and characteristics of IgG4related kidney disease.

Key words: IgG4-related kidney disease, tubulointerstitial nephritis, membranous nephropathyr, enal pathology