Abstract:

Abstract Objective: To investigate the short-term prognosis of people and kidney in AKI inpatients, as well as its related risk factors. Methodology: From Oct 2013 to Sep 2014, hospitalized patients (≥18 years old) in the First Affiliated Hospital of Nanjing Medical University according with AKI (KDIGO, 2012) criteria were enrolled into this retrospective study. Survival of AKI patients in 30 days after AKI diagnosis and prognosis of kidney when discharged were both observed, and its related risk factors were also analyzed. Results: (1) The incidence of AKI in hospitalized patients was 1.6%. Ratio of male to female was 2.03:1, average age was (63.2 ± 37.2), and median hospital stay was 18d. In-hospital mortality and 30d mortality of AKI patients was accounted for 15.8% and 35.4%, respectively. Patients discharged with complete renal recovery, partial renal recovery and no recovery was accounted 52.0%, 14.5% and 33.5%, respectively. (2) Age, history of chronic liver disease and oliguria, combined with extra-renal organ failure, malignancy and pulmonary diseases were independent risk factors for 30d mortality of AKI patients. (3) Multivariate analysis showed that age, oliguria, extra-renal organ failure, RRT, AKI stage, higher total bilirubin , lower hemoglobin and albumin level were independent risk factors for no recovery of renal. Conclusion: Age, oliguria and combined with other organs damage were risk factors for poor prognosis of AKI inpatients. Thus, renal function should be closely monitored. Also, prevention and early detection would be helpful to reduce risk of AKI prognosis.

Key words: acute kidney injury, inpatients, prognosis, risk factors