Abstract:

ABSTRACT It has been founf that the fluid resuscitation may be benefit to hemodynamic goals, however, it needs to be weighed against the harm associated with fluid overload. The composition of intravenous fluid may affect the risk of AKI. Hydroxyethyl starches increase the risk of severe AKI in ICU patients. Isotonic saline has been associated with greater incidence of AKI and in the reduction of renal perfusion in comparison to balanced solutions. In critcally ill patients with, or at risk of AKI, clinicians should avoid starch and possibly, saline solutions.

Key words: acute kidney injury, fluid resuscitation, hydroxyethyl starch, isotonic saline