Abstract: Ｏｂｊｅｃｔｉｖｅ：To analyze risk factor and prognosis of acute kidney injury（AKI) after coronary artery bypass grafting（CABG).
Ｍｅｔｈｏｄｏｌｏｇｙ：Clinical data of 1 449 patients under went CABG were analyzed retrospectively.The risk factors of AKI were analyzed by logistic regression.
Ｒｅｓｕｌｔｓ：There were 132 cases (91%) met the criteria of AKI after CABG,25 cases (189%) of them died within 30 days after the operation,the mortality was significantly higher than those without AKI（02%）.Logistic regression analysis showed that，postoperative pneumonia (OR=4557,95% CI 21869499),ventilator application time >36h (OR=3953,95% CI  23166748),reintubation (OR=4038,95% CI 145511202),incision infection (OR=5605,95% CI 235413345),cardiopulmonary bypass time>2h (OR=1754,95% CI  11152759) (P<005) were independent risk factors for AKI after CABG.
Ｃｏｎｃｌｕｓｉｏｎ：
AKI after CABG significantly increase the mortality of patients,independent risk factor of AKI  includes CPB and ventilator time,postoperative pneumonia and incision infection.

Key words: coronary artery bypass grafting, acute kidney injury, mortality, risk factors