Chinese Journal of Nephrology, Dialysis & Transplantation ›› 2019, Vol. 28 ›› Issue (4): 324-329.DOI: 10.3969/j.issn.1006-298X.2019.04.005
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Objective:To observe the incidence,clinical characteristics and risk factors of acute kidney injury (AKI) after cardiac surgery in our hospital,and provide evidence for better understanding and early intervention. Methodology:Retrospective analysis of patients with cardiac surgery from July 2017 to June 2018 in the First Affiliated Hospital of Xi′an Jiaotong University,screening patients with AKI and nonAKI recording their clinical data and analyzing risk factors. Results:Five hundred seventyfive patients were involved,AKI developed in 177 (3078%) patients,whereas 417% of them received renal replacement therapy.Patients with AKI had significant higher mortality than patients without AKI (1017% vs 05%,P<0001). The incidence of AKI stage 1,2,and 3 was 1913%(110/575),522%(30/575),and 643%(37/575) respectively,and the mortality was 272%(3/110),10%(3/30) and 3243%(12/37).There was a statistically significant difference in mortality between three groups(P<0001). Multivariate Logistic regression analysis showed that cardiopulmonary bypass (OR=1436,95%CI 1168~1765),advanced age(OR=7807,95%CI 1338~45563),previous cardiac surgery (OR=7807,95%CI 1338~45536),high level of preoperative blood Cystatin C (OR=3576,95%CI 139~9197),perioperative infection (OR=1436,95%CI 1168~1765) and intraoperative cardiopulmonary bypass time (OR=1457,95%CI 1077~1971)were the independent risk factors of AKI after cardiac surgery. The occurrence of AKI after cardiac surgery was mainly within 24 hours after surgery,accounting for 8023% of AKI patients. Conclusion: AKI can occur early after cardiac surgery in 3078% of patients.AKI has a significantly increased mortality compared with nonAKI patients.It should be alert to its risk factors and early intervention.
Key words: acute kidney injury, risk factors, morbidity, cardiac surgery, cardiopulmonary bypass
XUE Jinhong,HU Shuqin,CHEN Lei, et al. Characteristic of cardiac surgery patients with acute kidney injury[J]. Chinese Journal of Nephrology, Dialysis & Transplantation, 2019, 28(4): 324-329.
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URL: http://www.njcndt.com/EN/10.3969/j.issn.1006-298X.2019.04.005
http://www.njcndt.com/EN/Y2019/V28/I4/324