Abstract:

Ｏｂｊｅｃｔｉｖｅ：To explore the prognosis of organ donation after citizen death(DCD) in  kidney transplantation.
Ｍｅｔｈｏｄｏｌｏｇｙ：The data of 546 cases of DCD kidney transplantations performed in Third Medical Center, General Hospital of the Chinese Peoples Liberation Army between June 2013 and July 2018 was retrospectively reviewed. The 516 donors were aged from 5 to 68 (424±161) years,including 399 males and 117 females; the main causes of death were cerebral apoplexy and brain trauma. Single kidney from 20 children were given to children or lowweight adult recipients. Of the 546 recipients, 393 were males and 153 were females, with an average age of 11 to 70 (417±119) years. The quality of donor kidney, immune induction protocol, grafts function, complications, survival rate of recipient/kidney, and survival rate of special donor and special recipient were analyzed.
Ｒｅｓｕｌｔｓ：None of primary graft nonfunction occurred.Delayed graft function (DGF) occurred in 36 cases (66%) and acute rejection occurred in 28 cases (51%). 42 patients (77%) were suffed from pulmonary infection and 10 cases died. 18 patients lost their kidney function. The prognosis of recipients from children and the elderly donors were satisfactory; The incidence of DGF(429%) was higher in recipents from 14 acute renal injury donors related with rhabdomyolysis syndrome. There was no tumors recurrence in 22 recipients from nervous system tumors. The overall survival rate of person and kidney was 972% and 939%. The 1,3 and 5year survival rate of person and kidney were 985%, 969%,893% and 965%, 927% and 856% respectively.
Ｃｏｎｃｌｕｓｉｏｎ：The prognosis of DCD recipients and grafts were satisfactory. The main cause of death were pulmonary infection. Prognosis of specific kidney donors and recipients deserves attention.

Key words: organ donation after citizen death, kidney transplantation, prognosis