ISSN 1006-298X      CN 32-1425/R

Chinese Journal of Nephrology, Dialysis & Transplantation

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Clinical outcome of kidney transplantation from donation after citizens death

  

  • Online:2020-06-28 Published:2020-07-07

Abstract: Objective:To analyze  clinical outcome of kidney transplantation from organ donation after citizen′s death(DCD),and to evaluate  quality of DCD kidney and prognosis  of kidney transplantation recipients.
Methodology:The clinical data of DCD donors and kidney transplant recipients were retrospectively studied to observe the quality score of donor kidney,kidney function recovery,perioperative complications,delayed graft function (DGF), incidence of perioperative graft loss and longterm followup.
Results:The 114 cases of DCD were successfully administered,with warm ischemia time (56±22) min and cold ischemia time (65±16) h.Nonmarginal donors (grade A+B) accounted for 9211%,while marginal donors (grade C+D) accounted for 789%.The donor kidney was successfully obtained,perfused,preserved and repaired.Among 228 patients with end stage kidney disease who received DCD donor kidney transplantation,211 of them recovered successfully during the perioperative period,and their renal function returned to normal 6~14 days after surgery.The incidence of DGF was 354% (8/228),and renal function gradually recovered and discharged from hospital 20~45 days after surgery.The graft was removed in 1  primary nonfunctional recipient and 3 recipients with renal artery rupture and hemorrhage,the perioperative graft loss rate was 175% (4/228).None of the recipients died perioperatively.During the followup,213 recipients have stable graft renal function,8 recipients have graft renal failure,and 3 recipients died.
Conclusion:
The overall clinical outcome of DCD donors for kidney transplant  is good,but there are still some risks and complications.

Key words: kidney transplantation, donation after citizen′s death, clinical outcome