ISSN 1006-298X      CN 32-1425/R

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肾脏病与透析肾移植杂志 ›› 2013, Vol. 22 ›› Issue (1): 48-52.

• 论文 • 上一篇    下一篇

蛋白质组学在人类疾病研究中的应用

  

  • 出版日期:2013-02-28 发布日期:2013-03-19

The application of proteomics to the study of human disease

  • Online:2013-02-28 Published:2013-03-19

摘要:

摘要:蛋白质组学是后基因组时代生命科学研究的热点和前沿领域,应用蛋白质组学对临床疾病进行研究,不仅可从蛋白质水平上揭示疾病的本质,还有助于全面探讨其病理生理机制,寻找诊断和预后标志物,发现药物治疗靶点。目前蛋白质组学在肿瘤、心血管疾病、肾脏病等领域得到了广泛应用。

关键词: 蛋白质组学  , 肿瘤   , 心血管病  , 肾脏病

Abstract:

ABSTRACT Proteomics is a hot and frontier area of life science in post-genomic era. The application of proteomics to the study of human disease is useful to reveal the essence of disease from the level of protein, explore its pathophysiological mechanisms comprehensively, find diagnostic and prognostic biomarker, and discovery therapeutic target. In recent years, proteomics has been widely used in the field of cancer, cardiovascular and kidney disease.

Key words: proteomics , cancer , cardiovascular disease , kidney disease