ISSN 1006-298X      CN 32-1425/R

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肾脏病与透析肾移植杂志 ›› 2025, Vol. 34 ›› Issue (2): 158-162.DOI: 10.3969/j.issn.1006-298X.2025.02.012

• 医学继续教育 • 上一篇    下一篇

肾脏老龄化的特征和病理生理

  

  • 出版日期:2025-04-28 发布日期:2025-05-07

The characteristics and pathophysiology of kidney aging

  • Online:2025-04-28 Published:2025-05-07

摘要: 当今社会已经逐步进入老龄化,在老年人群中,慢性肾脏病和急性肾损伤的发生风险显著增加。老年人机体各系统和器官机能老化,多病共患,多重用药加重肾脏负担。因此,理解肾脏衰老特征,准确进行老年患者肾功能的评估对于老年病和肾脏病医师的临床诊疗和医学科研工作具有重要意义。本文复习相关文献,就肾脏老龄化的特征和病理生理研究进展作一综述。


关键词: 肾脏衰老, 老年医学, 慢性肾脏病

Abstract: Today's society is gradually entering an aging phase, with a significant increase in the risk of chronic kidney disease and acute kidney injury among the elderly population. The aging of various systems and organs in the elderly, along with the coexistence of multiple diseases and polypharmacy, exacerbates the burden on the kidneys. Therefore, understanding the characteristics of kidney aging and accurately assessing the renal function of elderly patients are of great significance for the clinical diagnosis and treatment as well as medical scientific research work of physicians in geriatrics and nephrology departments. This article reviews relevant literature and provides a comprehensive overview of the characteristics of kidney aging and the research progress in pathophysiology.


Key words: kidney aging, geriatrics, chronic kidney disease