ISSN 1006-298X      CN 32-1425/R

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肾脏病与透析肾移植杂志 ›› 2018, Vol. 27 ›› Issue (3): 290-293.DOI: 10.3969/j.issn.1006-298X.2018.03.020

• 论文 • 上一篇    下一篇

肾移植后轻链沉积病

  

  • 出版日期:2018-06-28 发布日期:2018-06-29

Light chain deposition disease after renal transplantation

  • Online:2018-06-28 Published:2018-06-29

摘要:

中年男性患者,肾移植术后血清肌酐升高,中等量蛋白尿和少量镜下血尿,肾活检组织学为肾小球结节样病变,免疫病理κ轻链弥漫分布于肾小球系膜区、毛细血管袢,肾小管基膜和间质血管壁,超微结构观察肾小球系膜区、毛细血管袢基膜内侧、肾小管基膜外侧、间质及小动脉壁见细颗粒状电子致密物沉积,诊断为移植肾轻链沉积病。

关键词: 轻链沉积病, 肾移植, 肾活检

Abstract:

A 49yearold man presented with renal insufficiency,moderate proteinuria and mild hematuria 2 years after renal transplantation.Renal biopsy showed glomerular nodular lesions,with κ light chain diffusely distributed in the mesangial area,GBMs,TBMs and vessel walls.The final diagnosis was light chain deposition disease in renal graft.

Key words: light chain deposition disease, renal transplantation, renal biopsy