关键词: 肾移植, 维生素D, 维生素D受体, 肌肉减少症, 移植后糖尿病, 排斥反应, 感染

Abstract: Vitamin D is a kind of micronutrient and hormone to maintain the normal physiological function of the human body, which activates VDR through various effects to play systemic and local roles. Vitamin D active forms and VDR gene polymorphisms are closely related to the occurrence of complications after kidney transplantation. In addition to regulating calcium and phosphorus metabolism and cardiovascular diseases in kidney transplantation recipients, vitamin D and its receptors also play an irreplaceable role in regulating the occurrence of bone abnormalities, sarcopenia, diabetes, rejection and infection in kidney transplantation recipients. This article reviews the role of vitamin D and receptors in the complications after kidney transplantation, and discusses the role of vitamin D and its analogues as adjunct agents after kidney transplantation and vitamin D receptors as therapeutic targets in the prevention and treatment of complications in kidney transplantation recipients.

Key words: kidney transplantation, vitamin D, vitamin D receptor, sarcopenia, posttransplantation diabetesrejection reaction, infection