Abstract:

：To investigate correlation factors of abdominal aortic calcification (AAC) in maintenance hemodialysis (MHD) patients with refractory secondary hyperparathyroidism(rSHPT). 
Ｍｅｔｈｏｄｏｌｏｇｙ：From May 2014 to January 2016, rSHPT patients without parathyroidectomy, in ChinaJapan Friendship Hospital were enrolled. The demographic data and biochemical data were collected, including intact parathyroid hormone (iPTH), calcium (Ca), phosphorus (P),Bone mineral density (BMD) were measured using dual Xray absorptiometry (DXA)，AAC was evaluated using lateral Xray plain films of abdomen. AAC severity was classified as absent (AAC=0), mild (1≤AAC score≤5), and moderate to severe (AAC score>6).
Ｒｅｓｕｌｔｓ：Eightytwo rSHPT patients were included, 63.4% of them had AAC. Compared with absent calcification group, patients in the other two groups were elder (P<0001), the dialysis time was longer (P<005), and Ctelopeptide of type I collagen(CTX) level in the absent calcification group was higher than the other groups (P<005). AAC was more severe in males (P<005). Multiple linear regression analysis shows that AAC was positively correlated with age (r=0042，P<0001) and serum phosphorus (r=0438，P=0045), and negatively with CTX (r=-0100，P=0035).
Ｃｏｎｃｌｕｓｉｏｎ：634% of MHD patients with rSHPT presented with AAC, and AAC may correlate with age, male, serum phosphorus and CTX.