Abstract: Ｏｂｊｅｃｔｉｖｅ：To analyze the characteristics and drug resistance of pathogenic bacteria cultured in renal intensive care unit (RICU) to provide guidance for treatment of infection in severe patients with kidney disease.
Ｍｅｔｈｏｄｏｌｏｇｙ：The distribution of pathogenic bacteria and the results of drug sensitivity test in RICU from January 1,2015 to December 31,2019 were retrospectively analyzed.
Ｒｅｓｕｌｔｓ：559 strains of pathogenic bacteria were cultured in 311 patients,There are 353 gramnegative bacteria (6315％),134 grampositive bacteria (2397％) and 72 fungi (1288％).A total of 76 pathogens were detected in blood culture,including 45 gramnegative bacteria (5921％),27 grampositive strains (3553％),4 fungi strains (526％).The common pathogens in blood culture were Klebsiella pneumoniae (1842％),Escherichia coli (1579％),Staphylococcus aureus (1447％) and Acinetobacter baumannii (1053％).Klebsiella pneumoniae and Acinetobacter baumannii resisted to carbapenems up to 70％ and 4545％ of Staphylococcus aureus are MRSA.A total of 244 pathogens were detected in sputum culture,including 188 gramnegative bacteria (7705％),18 grampositive strains (738％),38 fungi strains (1557％).The common pathogens were Acinetobacter baumannii (2090％),Klebsiella pneumoniae (1598％),Pseudomonas aeruginosa (1393％),and S.maltophilia (1066％).The drug resistance rate of Acinetobacter baumannii to carbapenem was more than 83％,Klebsiella pneumoniae was more than 61％,and the drug resistance rate of Pseudomonas aeruginosa carbapenem was about 50％.
Ｃｏｎｃｌｕｓｉｏｎ：
Gramnegative bacteria were the main pathogens in RICU patients,and the detection rate of drugresistant bacteria was high.