关键词: 系统性红斑狼疮, 狼疮肠系膜血管炎, 急性胰腺炎, T细胞亚群

Abstract: A 17-year-old female with systemic lupus erythematosus, who presented with nephrotic syndrome at onset, developed lupus encephalopathy, mesenteric vasculitis, and acute pancreatitis during treatment. She received methylprednisolone pulses and cyclophosphamide, plasma exchange, and hemofiltration and sequential B cell-targeting therapies, and achieved complete remission. Identification of T cell subpopulation changes is helpful in this case for the differential diagnosis of severe SLE complicated with multi-system involvement and other complications, such as infection and adverse drug reactions.

Key words: systemic lupus erythematosus, lupus mesenteric vasculitis, acute pancreatitis, T cell subpopulation