关键词: 亲属活体肾移植, 肾功能延迟恢复, 危险因素

Abstract: Ｏｂｊｅｃｔｉｖｅ：Objective To analyze retrospectively the risk factors of delayed graft function (DGF) after living relative kidney transplantation.
Ｍｅｔｈｏｄｏｌｏｇｙ：205 pairs of donors and recipients receiving kinship living kidney transplantation admitted to our hospital from January 2015 to December 2021 were included in the study, and their clinical data were collected and analyzed. Including the matching of donor and recipient nationality, recipient nationality, gender, age, blood type, population reactive antibody, complement-dependent cytotoxicity, matching number of human leukocyte antigen, dialysis time, concomitant hypertension; Donor sex, age, preoperative creatinine level, donor glomerular filtration rate, concomitant hypertension, donor／recipient surface area ratio, warm and cold ischemia, and etiology of chronic renal failure. Univariate and multivariate logistic regression analysis were used to investigate the risk factors of DGF.
Ｒｅｓｕｌｔｓ：The incidence of DGF in relative living kidney transplantation recipients was 31.21％. Univariate analysis showed that: There were statistically significant differences in recipient nationality, complement-dependent cytotoxicity, donor glomerular filtration rate, donor concomitant hypertension, donor／recipient body surface area ratio, and cold ischemia time among groups (P<0.05). Multivariate regression analysis showed that: Minority recipients (OR=4.386, P=0.003), donor／recipient body surface area ratio <1 (OR=2.611, P=0.033) and donor GFR <40 mL／(min·1.73m2) (OR=9.725, P<0.001) were independent risk factors that directly affected the development of DGF.
Ｃｏｎｃｌｕｓｉｏｎ：Minority recipients, donor／recipient body surface area ratio <1 and donor GFR <40 mL／(min·1.73 m2) are important factors affecting DGF.

Key words: living relative kidney transplantation, delayed graft function, risk factors