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肾脏病与透析肾移植杂志

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新型冠状病毒肺炎疫情下透析治疗面临的挑战与对策

  

  • 出版日期:2020-10-28 发布日期:2020-10-30

Challenges and emergency procedures   in dialysis patients with COVID-19

  • Online:2020-10-28 Published:2020-10-30

摘要: 新型冠状病毒肺炎(简称新冠肺炎)是由新型冠状病毒(SARSCoV2,简称新冠病毒)引起并广泛传播的呼吸道疾病,具有极强的传染性。20200311,世界卫生组织宣布新冠肺炎已构成全球大流行。新冠病毒主要传播途径是呼吸道飞沫与密切接触,人群普遍易感。新冠病毒通过激发炎症因子风暴、器官交互对话以及系统性作用途径造成多器官系统损害。最新研究指出透析患者合并新冠肺炎近期死亡率高达30%,且腹膜透析(PD)合并新冠肺炎透出液可检出新冠病毒。本文结合现有文献,综述新冠肺炎疫情下透析技术面临的挑战与应对措施。

关键词: 新型冠状病毒肺炎, 新型冠状病毒, 透析

Abstract: Corona virus disease 2019 (COVID19) is a lifethreatening and highly contagious respiratory condition caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV2).On 11 March 2020,the World Health Organization announced that COVID19 has become a global pandemic.The main route of transmission is respiratory droplets and close contact.The potential mechanisms of organ involvement in these patients can be didactically divided into three aspects:cytokine damage,organ crosstalk and systemic effects.Mortality among hospitalized hemodialysis patients diagnosed with COVID19 was 30%,and literature demonstrated SARSCoV2 positivity in peritoneal dialysate.The discussion herein will review challenges and opportunities of dialysis in the global pandemic of COVID19.