Abstract:

A 44 yearold man who had worked in Africa，presented with chills and persisted fever，progressing to multiple organ dysfunction rapidly. His blood test found ringstage Plasmodium. The kidney biopsy revealed interstitial inflammatory cellular infiltration and tubulitis with acute tubular injury. The final diagnosis for the case was severe malaria，acute kidney injury（AKI），multiple organ dysfunction syndrome（MODS）.

Key words: severe malaria, acute kidney injury, multiple organ dysfunction syndrome