ISSN 1006-298X      CN 32-1425/R

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肾脏病与透析肾移植杂志 ›› 2014, Vol. 23 ›› Issue (6): 573-576.

• 论文 • 上一篇    下一篇

血浆分离技术在肾移植中的应用

  

  • 出版日期:2014-12-28 发布日期:2014-12-31

Therapeutic Plasma Apheresis in Kidney Transplantation

  • Online:2014-12-28 Published:2014-12-31

摘要:

摘 要 血浆分离技术包括血浆置换、双重血浆滤过和免疫吸附。在肾移植领域,血浆分离技术主要用于清除受者体内的供者特异性抗体和其他致病因子或抗体。因此,临床上用于治疗肾移植术后抗体介导的排斥反应、移植后复发性局灶节段性肾小球硬化;同时该技术在肾移植术前致敏受者的处理、ABO血型不相容的肾移植中也起到关键作用。本文就血浆分离技术在肾移植中的应用做一综述。

关键词: 血浆分离, 肾移植, 供者特异性抗体

Abstract:

ABSTRACT Therapeutic plasma apheresis includes plasmapheresis, double filtration plasmapheresis and immunoadsorption. In renal transplantation, therapeutic plasma apheresis has been widely used in the removal of donor specific antibodies and other circulating factors and antibodies. It has been used to treat antibody mediated rejection and recurrent focal segmental glomerulosclerosis after kidney transplantation; to treat sensitized patients before transplantation. Furthermore, therapeutic plasma apheresis plays an important part in ABO-incompatible transplantation, which helps to expand the donor pool for living kidney donation.
Key words

Key words: apheresis, renal transplantation, donor specific antibody