ISSN 1006-298X      CN 32-1425/R

导航

肾脏病与透析肾移植杂志 ›› 2014, Vol. 23 ›› Issue (4): 354-359.

• 论文 • 上一篇    下一篇

巨噬细胞与肾脏疾病

  

  • 出版日期:2014-08-28 发布日期:2014-09-02

Macrophage and kidney diseases

  • Online:2014-08-28 Published:2014-09-02

摘要:

摘要:巨噬细胞浸润是多种肾脏疾病的常见病理表现。根据其表面标志及功能的不同,巨噬细胞可以被分为不同的亚型。研究发现肾组织中巨噬细胞的亚型与肾脏损伤、修复抑或纤维化的关系非常密切。本文对近年来有关巨噬细胞的生物学特性、功能以及与肾脏病关系的研究进展进行了综述。

关键词: 巨噬细胞, 肾脏病

Abstract:

ABSTRCT: Macrophage infiltration is a common feature of various renal diseases. It may be identified as different subsets in accordance with their phenotype and function. Emerging evidences suggest that the subset of infiltrating macrophage is closely correlated to renal injury, repair or fibrosis. Here the biological feature, function and associated mechanisms of macrophage and its relationship with renal diseases are reviewed.

Key words: Macrophage, Kidney disease