Abstract: Acute kidney injury (AKI) is a clinical syndrome characterized by a rapid increase in serum creatinine, a rapid decline in glomerular filtration rate, or urine volume, with high morbidity and mortality. However, the treatment options for AKI are still limited at present. Remote ischemic preconditioning (rIPC) is a non-pharmacological and effective treatment modality to improve renal function in AKI patients. This article aims to review the therapeutic effect and underlying mechanism of rIPC on different types of AKI and provide a theoretical basis for the clinical application of rIPC.

Key words: remote ischemic preconditioning, acute kidney injury, therapeutic effect, mechanism