Abstract: Peritoneal dialysis (PD) is one of the treatment methods for end-stage kidney disease. It uses the semipermeable membrane characteristics of the peritoneum to remove metabolites in the body and correct the imbalance of water and electrolyte through continuous replacement of peritoneal dialysate. Recent studies have shown that polymorphisms of multiple molecules are correlated with peritoneal function, thereby affecting the prognosis of patients, which has suggestive significance for the prescription and prognosis of dialysis patients. The purpose of this article is to review the current research progress of molecular genetic mechanism related to peritoneal transport function.

Key words: peritoneal dialysis, peritoneal ultrafiltration, molecular genetic mechanism