Abstract:

Ｏｂｊｅｃｔｉｖｅ：Acute kidney injury (AKI) is a common complication of rhabdomyolysis. The aim of this study was to investigate the etiological factors，clinical characteristics，treatment and prognosis of  acute kidney injury caused by rhabdomyolysis.
Ｍｅｔｈｏｄｏｌｏｇｙ：A total of thirty four patients with rhabdomyolysis induced AKI fulfilled the inclusion criteria was enrolled into this retrospective study. Their etiological factors，clinical characteristics，treatment and prognosis were investigated.
Ｒｅｓｕｌｔｓ：They were 26 males and 8 females with a median age of 38 years old (ranged from 19 to 72yrs). The causes of NHL include heat stroke (9 cases), strenuous muscular exercise (6 cases)，muscles compression (3 cases)，and trauma (3 cases). Other  causes  included lipid-lowering  agents，hypothyroidism，snake venom，wasp sting，infections，hypokalemia1，and epilepsy.  All of 34 cases had an increasing level of serum myohemoglobin and creatine phosphokinase. 28　patients presented anuria，oliguria，and teacolored urine; 8 patients showed multiple organ dysfunction syndrome. Among them, 24 patients were required continuous blood purification (CBP) during the treatment. In followup, 31 cases survived and recovered their renal function, and only 3 cases died of multiple organ dysfunction syndrome.
Ｃｏｎｃｌｕｓｉｏｎ：Rhabdomyolysis has various etiological factors. The most frequent cause of rhabdomyolysis was heat stroke and strenuous muscular exercise. Early diagnosis，comprehensive treatment，including early effective blood purification，can improve the curative effect. Prognosis was good in most patients with acute renal failure from rhabdomyolysis.