ISSN 1006-298X      CN 32-1425/R

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肾脏病与透析肾移植杂志 ›› 2014, Vol. 23 ›› Issue (6): 582-586.

• 论文 • 上一篇    

干细胞移植后贫血、血小板减少、蛋白尿

  

  • 出版日期:2014-12-28 发布日期:2014-12-31

Anemia,thrombocytopenia and proteinuria after blood stem cell transplantation

  • Online:2014-12-28 Published:2014-12-31

摘要:

摘 要 青年女性患者,因重度再生障碍性贫血行同胞全相合造血干细胞移植,3月后出现溶血性贫血、血小板减少、大量心包积液,水肿、蛋白尿,两次肾活检病理提示血栓性微血管病,诊断为移植物抗宿主病(GVHD)相关的血栓性微血管病(TMA)。

关键词: 干细胞移植, 移植物抗宿主病, 血栓性微血管病

Abstract:

Abstract A young female patient with severe aplastic anemia, underwent allogeneic peripheral blood stem cell transplantation from a fully HLA-matched sibling. Three months later, she suffered from hemolytic anemia, thrombocytopenia, pericardial effusion, edema and proteinuria. Twice renal biopsies disclosed graft-versus-host disease(GVHD)associated thrombotic microangiopathy.

Key words: blood stem cell transplantation, graft-versus-host disease, thrombotic microangiopathy