ISSN 1006-298X      CN 32-1425/R

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肾脏病与透析肾移植杂志 ›› 2014, Vol. 23 ›› Issue (1): 73-78.

• 论文 • 上一篇    下一篇

环境因素导致肾脏损害的表观遗传学机制

  

  • 出版日期:2014-02-28 发布日期:2014-02-25

Epigenetic Mechanisms of Environmental Factors-induced Kidney Injury

  • Online:2014-02-28 Published:2014-02-25

摘要:

摘要   化学物质、物理射线、生物因素、饮食等环境因素可以导致肾脏的损伤。表观遗传学是当今各个领域研究的热点问题。近期的研究发现,化学毒物环境的暴露可以通过表观遗传学的改变引起肾脏损伤,本文将就此作一综述。

关键词:  , 环境暴露,  , 肾脏损伤,  , 表观遗传学

Abstract:

Research Institute of Nephrology, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210016, China.
ABSTRACT Chemicals, radiations, biological factors, diet and other environmental factors can cause kidney damage. Epigenetics is the emerging field of biological and medical sciences, and recent studies have shown that exposure to harmful environmental factors causes kidney injury by epigenetic mechanisms. We review the recent progress in the field.

Key words: environmental exposure,  renal damage,  epigenetics