ISSN 1006-298X      CN 32-1425/R

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肾脏病与透析肾移植杂志 ›› 2012, Vol. 21 ›› Issue (2): 183-189.

• 论文 • 上一篇    下一篇

微炎症状态与腹膜透析

  

  • 出版日期:2012-04-28 发布日期:2012-04-18

Microinflammation state and peritoneal dialysis

  • Online:2012-04-28 Published:2012-04-18

摘要:

长期接受腹膜透析的终末期肾病患者,体内始终存在着微炎症状态,研究表明微炎症状态与慢性肾脏病患者常见的并发症密切相关,如心血管疾病和营养不良,监测体内炎症因子水平可以预测死亡率及心血管事件的结局。本文综述了腹膜透析患者出现微炎症的原因、病理生理机制及防治措施。

Abstract:

Micro-inflammation state is observed in patients with end-stage renal disease (ESRD), especially those receiving long-term peritoneal dialysis (PD). In recent years, the inflammation is strongly associated with common complication of chronic kidney disease,such as cardiovascular disease and malnutrition。The level of inflammatory markers have been shown consistently to be a powerful predictor of mortality and adverse cardiovascular outcomes in patients with PD. In this article, the potential causes, pathophysiological mechanisms and control measures of micro- in?ammation in PD patients were reviewed.