ISSN 1006-298X      CN 32-1425/R

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肾脏病与透析肾移植杂志 ›› 2011, Vol. 20 ›› Issue (3): 263-269.

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环境内分泌干扰物与机体代谢紊乱

  

  • 出版日期:2011-06-30 发布日期:2011-08-08

Endocrine disrupting chemicals and metabolic disorders

  • Online:2011-06-30 Published:2011-08-08

摘要:

肥胖和2型糖尿病等代谢性疾病是影响人类健康的重大问题。环境内分泌干扰物与其发病关系密切。塑料、杀虫剂、二噁英等物质均可引起代谢紊乱,这些物质通过激素受体、外源性化合物受体和代谢受体等多种受体干扰正常机体代谢。

Abstract:

Metabolic disorders such as obesity and type-2 diabetes have been one of the major health problems all over the world. It is proved that endocrine disrupting chemicals may interfere with the normal metabolism. Plastics, pesticides and doxins can inappropriately activate some of the hormone receptors, the xenosensors, and the metabolic receptors, which then mediate the endocrine disruption.