Abstract: Ｏｂｊｅｃｔｉｖｅ：To investigate the effect of peritoneal dialysis (PD) adequacy on the cardiac structure and function among patients with endstage renal disease (ESRD),and the correlation between them.
Ｍｅｔｈｏｄｏｌｏｇｙ：A total of 99 patients with ESRD who were undergoing continuous ambulatory peritoneal dialysis (CAPD) from May 2016 to May 2019 in the First Affiliated Hospital of Soochow University were retrospectively enrolled in this study. They were divided into inadequate dialysis group of 45 patients (Kt/V<17 and total Ccr<50 L/173m2) and adequate dialysis group of 54 patients (Kt/V≥17 and total Ccr≥50 L/173m2). Baseline data,biochemical indicators and echocardiographic characteristics were collected. All  patients were followed up for 12 months to compare  differences of the parameters mentioned above. We also recorded the occurrence of PDrelated adverse events between two groups. Pearson or Spearman correlation analysis was used to explore  correlation between cardiac structure and function with PD adequacy.
Ｒｅｓｕｌｔｓ：The atrial diameter,interventricular septal thickness(IVS),left ventricular endsystolic diameter(LVSD),left ventricular enddiastolic diameter(LVDD),left ventricular posterior wall thickness(LVPW),left ventricular mass index(LVMI) and tricuspid regurgitation pressure in  adequate dialysis group were lower than those in  inadequate dialysis group,and  left ventricular ejection fraction(LVEF) was higher. Left atrial diameter(LAD) and IVS of  two groups were both higher than that at baseline after 12 months of followup (P<005). Correlation analysis shows that  PD adequacy has varying degrees of correlation with cardiac structure and function.
Ｃｏｎｃｌｕｓｉｏｎ：
Improving PD adequacy is of great significance for improving ventricular remodeling and maintaining cardiac function.