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肾脏病与透析肾移植杂志

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肠道菌群与肾移植

  

  • 出版日期:2020-02-28 发布日期:2020-03-19

Gut microbiota and kidney transplantation

  • Online:2020-02-28 Published:2020-03-19

摘要: 了解肾移植受者肠道菌群的构成及其变化对改善肾移植受者短期及长期预后具有重要的意义。现有研究显示肾移植受者存在肠道菌群失调的情况,特别是出现并发症时,通过改善肾移植受者肠道菌群失调来提高患者预后具有治疗前景。本文旨在阐述肠道菌群在肾移植的最新研究进展。

关键词: 肾移植, 肠道菌群, 并发症, 治疗

Abstract: The understanding of gut microboita constitution and its changes in kidney transplant recipients are of great significance in improving both shortterm and longterm kidney transplant prognosis. This review aims to elucidate the latest advances in gut microboita in kidney transplantation,including changes in gut microboita associated with transplantation,the interaction between gut microbiota and postoperative complications,and means to modulate the gut microboita through dietary adjustment,microecological agents and fecal microbial transplantation. Current research had proven gut dysbiosis in kidney transplant recipients,especially when there were complications. Improving the prognosis of kidney transplant recipients by modifying the gut microbiota is promising,but more largescale studies are needed to comfirm the clinical significance.