ISSN 1006-298X      CN 32-1425/R

导航

肾脏病与透析肾移植杂志

• 论文 • 上一篇    下一篇

原发性甲状旁腺功能亢进伴急性肾损伤

  

  • 出版日期:2019-10-28 发布日期:2020-01-07

Acute kidney injury due to primary hyperparathyroidisminduced hypercalcemic crisis

  • Online:2019-10-28 Published:2020-01-07

摘要: 老年女性患者,急性起病,反复出现干呕、纳差、多饮、多尿,伴双下肢多关节疼痛,近期有摔倒后桡骨骨折史。入院检查示高钙危象、血清肌酐升高、甲状旁腺激素明显升高,骨密度检查示严重骨质疏松,B超示甲状腺右叶下方囊实性肿块、左肾钙质沉着。经对症治疗,患者血钙下降、肾功能好转。转至外科行“右侧甲状旁腺腺瘤、双侧甲状腺全切除术”,术后病理示右侧甲状旁腺腺瘤、右侧甲状腺乳头状癌。

关键词: 高钙危象, 急性肾损伤, 原发性甲状旁腺功能亢进, 甲状旁腺腺瘤, 甲状腺乳头状癌

Abstract: 68yearold woman entered our hospital complaining of acute discomfort,obtaining dysemesia,anorexia,polydipsia,polyuria,and multiple arthralgia of both lower limbsSeveral weeks before admission,she suffered with right distal radius fracture after accidental fall.The blood test showed hypercalcemic crisis,elevated serum creatinine and parathyroid hormone (PTH)Bone density measurement showed severe osteoporosis.Doppler ultrasonography showed a cystic mass on the inferior pole of the right lobe of  thyroid and calcinosis in the left kidney.After symptomatic treatment,her calcium concentration decreased and renal function improvedShe received right parathyroidectomy and bilateral thyroidectomy,and the pathological examination confirmed right parathyroid adenoma and papillary thyroid carcinoma.