ISSN 1006-298X      CN 32-1425/R

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肾脏病与透析肾移植杂志 ›› 2018, Vol. 27 ›› Issue (4): 396-400.DOI: 10.3969/j.issn.1006-298X.2018.04.022

• 论文 • 上一篇    

系统性红斑狼疮伴抗磷脂综合征

  

  • 出版日期:2018-08-28 发布日期:2018-08-31

A patient with systemic lupus erythematosus and antiphospholipid syndrome

  • Online:2018-08-28 Published:2018-08-31

摘要:

青年女性系统性红斑狼疮患者,急性起病,表现为急性肾损伤、突发无尿、急性心功能不全伴贫血、血小板减少,抗心磷脂抗体等自身抗体阳性、补体减低,反复感染。短期内心瓣膜病变进展至重度二尖瓣返流。经肾脏替代治疗、行二尖瓣置换术后心肾功能改善。随访半年后尿量恢复正常,1年后摆脱透析。

关键词: 系统性红斑狼疮, 抗磷脂抗体, 二尖瓣返流, 心肾综合征

Abstract:

A 20yearold girl presented with acute kidney injury,suddenly anuria,acute heart failure,anemia and thrombocytopenia,with hypocomplementemia,positive  antiphospholipid antibody and recurrent infection.Mitral regurgitation deteriorated quickly within a short time.Renal and heart function improved after renal replacement therapy and mitral valve replacement surgery.Six months later,her urine volume returned to normal and she got off dialysis one year later.

Key words: lupus, antiphospholipid antibody, mitral regurgitation, cardio-renal syndrome