Castleman病变异型POEMS综合征

doi:10.3969/j.issn.1006-298X.2022.02.020

肾脏病与透析肾移植杂志 ›› 2022, Vol. 31 ›› Issue (2): 195-200.DOI: 10.3969/j.issn.1006-298X.2022.02.020

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Castleman病变异型POEMS综合征

出版日期:2022-04-28 发布日期:2022-04-21

Castleman disease variant of POEMS syndrome

Online:2022-04-28 Published:2022-04-21

摘要/Abstract

摘要： 30岁男性,因“水肿、蛋白尿2月余,腹胀、血清肌酐升高1月余”入院。患者于外院肾活检示“血栓性微血管病样病变”,给予对症治疗,但腹胀、肾功能不全进行性加重。转诊国家肾脏疾病临床医学研究中心发现多发淋巴结肿大、肝脾肿大、多浆膜腔积液、血管内皮生长因子升高,单克隆免疫球蛋白阴性。淋巴结活检符合Castleman病,最终确诊为Castleman病变异型POEMS综合征。

关键词: Castleman病变异型POEMS综合征, Castleman病, POEMS综合征, 多浆膜腔积液

Abstract: A 30yearold man was hospitalized for edema and proteinuria followed by progressive abdominal distension and renal dysfunction.His renal biopsy two months ago at the onset of illness revealed a thrombotic microangiopathy lesion.After admission to our hospital,comprehensive examinations were implemented and uncovered multiple lymphnodes enlargement,hepatosplenomegaly,polyserous effusions,elevated vascular endothelial growth factor (VEGF) level.But neither Mprotein nor clonal plasma cells were detectable.Lymph node biopsy confirmed Castleman Disease.Castleman disease variant POEMS syndrome was the final diagnosis.

Key words: Castleman disease variant POEMS syndromeCastleman disease, POEMS syndrome, polyserous effusion

周玉超, 许书添, 李世军. Castleman病变异型POEMS综合征[J]. 肾脏病与透析肾移植杂志, 2022, 31(2): 195-200.

ZHOU Yuchao, XU Shutian, LI Shijun. Castleman disease variant of POEMS syndrome[J]. Chinese Journal of Nephrology, Dialysis & Transplantation, 2022, 31(2): 195-200.

[1]	樊璠，梁丹丹，吴燕. Castleman病伴系统性淀粉样变性[J]. 肾脏病与透析肾移植杂志, 2018, 27(2): 196-200.
[2]	李世军，陈惠萍，涂远茂，等. POEMS综合征相关肾损害临床及病理特征[J]. 肾脏病与透析肾移植杂志, 2012, 21(5): 429-434.
[3]	徐峰,曾彩虹,刘志红. POEMS综合征相关肾损害——肾小球弥漫系膜溶解[J]. 肾脏病与透析肾移植杂志, 2012, 21(1): 88-91.

ISSN 1006-298X CN 32-1425/R

Castleman病变异型POEMS综合征

Castleman disease variant of POEMS syndrome

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