关键词: 血管紧张素Ⅱ,血管扩张性休克,脓毒性休克,升压药

Abstract: Vasodilatory shock is a type of shock characterized by extensive vasodilation. Patients with refractory vasodilatory shock who require large doses of vasoactive drugs to maintain blood pressure， resulting a high mortality rate. Excessive use of catecholamines will bring visceral ischemia, arrhythmia and other serious adverse consequences. The US Food and Drug Administration approved angiotensin Ⅱ for the treatment of vasodilatory shock based on the results of studies including a Phase Ⅲ clinical trial. This article reviews recent advances of angiotensin Ⅱ in vasodilatory shock.

Key words: angiotensin Ⅱ, vasodilatory shock, septic shock, vasopressors