ISSN 1006-298X      CN 32-1425/R

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肾脏病与透析肾移植杂志 ›› 2016, Vol. 25 ›› Issue (4): 390-393.DOI: 10.3969/cndt.j.issn.1006-298X.2016.04.019

• 论文 • 上一篇    下一篇

肾小球内皮细胞损伤伴系膜溶解

  

  • 出版日期:2016-08-28 发布日期:2016-08-31

Glomerular endothelial cell lesion with mesangiolysis

  • Online:2016-08-28 Published:2016-08-31

摘要:

老年男性患者,临床表现蛋白尿、血清肌酐轻度升高,伴有高血压,肾活检组织学改变为肾小球内皮细胞病变伴系膜溶解。该患者直肠癌术后肝脏转移,曾使用卡培他滨及贝伐珠单抗化疗。结合临床考虑贝伐珠单抗相关肾损害。

Abstract:

A 63yearold man presented with proteinuria, hypertension with an increase of serum creatinine. The patient was diagnosed as liver metastasis in 2013, and underwent chemotherapy and antiVEGF therapy. A renal biopsy showed glomerular endothelial cell lesion with mesangiolysis. The final diagnosis was glomerular disease related to bevacizumab.