ISSN 1006-298X      CN 32-1425/R

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肾脏病与透析肾移植杂志 ›› 2016, Vol. 25 ›› Issue (4): 375-380.DOI: 10.3969/cndt.j.issn.1006-298X.2016.04.016

• 论文 • 上一篇    下一篇

药物相关的肾小管-间质损伤

  

  • 出版日期:2016-08-28 发布日期:2016-08-31

Druginduced  renal tubularinterstitial diseases

  • Online:2016-08-28 Published:2016-08-31

摘要:

药物性肾小管间质损伤是许多药物治疗过程中常见的并发症,其病情轻重不一,从轻微、可逆性肾脏损害到终末期肾病不等,不同药物所引起的肾小管间质损伤的机制不同。本文将主要阐述药物相关肾小管间质损伤的不同临床表现、病理特点、发病机制、预防及治疗,以提高药物相关肾小管间质损伤的诊断与治疗水平。

Abstract:

Druginduced tubularinterstitial injury is a common complication in numerous medical procedures, with variable clinical presentations ranging from  mild, reversible injury of renal functions to Endstage renal disease. The mechanisms of druginduced tubularinterstitial diseases may differ from various drugs. To improve the diagnosis and treatment, this paper will review the clinical presentations, pathology, pathogenesis, prevention and treatment of the  druginduced tubularinterstitial diseases.