关键词: 具有肾脏意义的单克隆免疫球蛋白病, 临床病理特征, 诊断, 治疗

Abstract: Monoclonal gammopathy of renal significance (MGRS) is different from monoclonal gammopathy of undetermined significance (MGUS). Nephrotoxic monoclonal immunoglobulins produced by MGRS cause irreversible damage to human organs, especially kidneys. There is a high recurrence rate in MGRS patients after renal transplantation. Therefore, early identification of MGRS and treatments targeting malignant proliferative foci (B cell／plasma cell) are of great significance for saving organ function and improving prognosis.

Key words: monoclonal gammopathy of renal significance, clinicopathological features, diagnosistreatment