关键词: 腹膜透析, 生存率, 代谢综合征, COX分析

Abstract:

ABSTRACT Objective: The regular follow-up materials were collected retrospectively, the relationship of metabolic syndrome（MS）and the mortality in patients with peritoneal dialysis (PD) was investigated. Methodology: One hundred and eight patients with PD were enrolled in this study, and followed up regularly from July 2007 to July 2008. The definition of metabolic syndrome was modified NCEP ATP III, 2001 diagnosis standard definition. According to whether or not diagnosis as MS, they were divided into MS group and without MS group. The total survival estimate Kaplan-Meier method, and Cox ratio for mortality risk model the comparison of the relative risk was used to evaluate the survival rate and mortality in different two groups. Results: There were 44 cases (40.7%) patients with the metabolic syndrome on baseline. The cumulative survival rate was 76.9% in MS group, while 46.5% in non-MS group, two groups of survival after Log-Rank inspection: P=0.001. Calibration confounding factors by multiple factors Cox proportion risk analysis, metabolic syndrome relative risk was RR:2.336 (95% CI, 1.078 to 4.070; P = 0.029). Conclusion: The peritoneal dialysis patients with metabolic syndrome have a high mortality, which is a predicting independent risk factors for survival.

Key words: Peritoneal dialysis , Survival rate , Metabolic Syndrome  , COX analysis