ISSN 1006-298X      CN 32-1425/R

Chinese Journal of Nephrology, Dialysis & Transplantation ›› 2016, Vol. 25 ›› Issue (3): 291-295.

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Renal Impairment in Gitelman's Syndrome

  

  • Online:2016-06-28 Published:2016-07-04

Abstract:

Abstract: A 31-year-old woman with recurrent weakness in the limbs and hypotension or normotension was admitted our hospital. Blood tests demonstrated elevated serum creatinine, hypokalemic hypochloremic metabolic alkalosis, normomagnesemia and elevated levels of renin and aldosterone. Urinalysis revealed renal loss of potassium and hypocalciuria. There was no proteinuria or hematuria. Renal biopsy showed hyperplasia of juxtaglomerular apparatus, severe interstitial fibrosis and tubular atrophy and mild acute tubular injury. Finally, we considered the renal impairment in the patient was related to Gitelman’s syndrome.
Key words

Key words: Gitelman’s syndrome, juxtaglomerular apparatus, Renal biopsy