Abstract:

ABSTRACT A 40 year-old man presented with proteinuria，hypoalbuminemia，hypertension， and normal renal function for 17 months. The patient’s father died from nephritic syndrome. A renal biopsy showed amyloidosis characterized by obliterative glomerular involvement without interstitial or vascular deposition，in which the amyloid deposits stained only for apolipoprotein A-I by immunofluorescense．The final diagnosis was hereditary apolipoprotein A-I related amyloidosis．

Key words: Apolipoprotein A-I, amylodosis, renal biopsy