Abstract: Ｏｂｊｅｃｔｉｖｅ：To analyze the clinical characteristics and prognosis of hospitalized renal transplant recipients infected with Coronavirus Disease 2019 (COVID-19).
Ｍｅｔｈｏｄｏｌｏｇｙ：The renal transplant recipients with COVID-19 who were hospitalized in National Clinical Research Center of Kidney Diseases, Jinling Hospital during the peak period of COVID-19 in China from December 2022 to February 2023 were retrospectively observed, the general information of patients, comorbidities, immunosuppressants, laboratory findings, and prognosis were collected and analyzed.
Ｒｅｓｕｌｔｓ：A total of 72 cases were observed, including 42 moderate cases (58.3％), 16 severe cases (22.2％), and 14 critically severe cases (19.5％), with an average age of 48.6. 80.6％ patients had hypertension, 33.3％ had diabetes. 91.7％ of the patients had decreased lymphocytes. As the severity of the disease worsen, proportion of concurrent fungal and bacterial infections gradually increased. Eight patients (11.1％) died, all of whom were critically severe group. Regression analysis found that fungal infection (HR 10.55,95％CI 1.040~107.112, P=0.046) and bacterial infection (HR 26.934,95％CI 2.084~348.161, P=0.012) were risk factors for death.
Ｃｏｎｃｌｕｓｉｏｎ：Renal transplant recipients with COVID-19 observed in our research had many comorbidities and severe lymphopenia, concurrent of fungal and bacterial infection were risk factors for death.

Key words: renal transplant recipient, COVID-19, complication, prognosis