慢性B淋巴细胞白血病、肾脏淀粉样变性合并C3肾小球病

肾脏病与透析肾移植杂志 ›› 2016, Vol. 25 ›› Issue (2): 195-200.

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慢性B淋巴细胞白血病、肾脏淀粉样变性合并C3肾小球病

出版日期:2016-04-28 发布日期:2016-05-04

B-cell chronic lymphocytic leukemia, kidney amyloidosis with C3 glomerulopathy

Online:2016-04-28 Published:2016-05-04

摘要/Abstract

摘要：

摘要 68岁男性患者，临床表现肾病综合征，血清单克隆游离轻链比例异常，免疫固定电泳见κ型IgG单克隆免疫球蛋白条带，肾活检病理提示肾淀粉样变性合并C3肾小球病，间质大量CD20阳性细胞浸润。骨髓穿刺及活检提示淋巴浆细胞高度增生。结合临床、病理最终诊断慢性B淋巴细胞白血病、肾淀粉样变性合并C3肾小球病。

关键词: B淋巴细胞白血病, 肾淀粉样变性, C3肾小球病

Abstract:

ABSTRACT A 68-year-old man was admitted for nephrotic syndrome. His serum free light chain ratio was abnormal, and immunofixation electrophoresis test was positive. His renal biopsy revealed amylodiosis with C3 deposition, renal interstitial infiltrating lymphocytes that were positive of CD20. Bone marrow puncture and biopsy revealed abnormal B-cell lymphoproliferation. The final diagnosis for the case was B-cell chronic lymphocytic leukemia (B-CLL), renal amyloidosis with C3 glomerulopathy.

Key words: B-cell chronic lymphocytic leukemia, renal amyloidosis, renal amyloidosis, C3 glomerulopathy

张志宏|谢红浪|刘志红. 慢性B淋巴细胞白血病、肾脏淀粉样变性合并C3肾小球病[J]. 肾脏病与透析肾移植杂志, 2016, 25(2): 195-200.

ZHANG Zhihong|XIE Honglang|LIU Zhihong. B-cell chronic lymphocytic leukemia, kidney amyloidosis with C3 glomerulopathy[J]. Chinese Journal of Nephrology, Dialysis & Transplantation, 2016, 25(2): 195-200.

[1]	周巧玲\|王睿苓. 浅谈C3肾小球病[J]. 肾脏病与透析肾移植杂志, 2016, 25(2): 153-154.
[2]	曾彩虹. C3肾小球病的认识与诊断[J]. 肾脏病与透析肾移植杂志, 2016, 25(2): 155-156.
[3]	于峰. C3肾小球病的认识过程及诊治现状[J]. 肾脏病与透析肾移植杂志, 2016, 25(2): 157-158.

ISSN 1006-298X CN 32-1425/R

慢性B淋巴细胞白血病、肾脏淀粉样变性合并C3肾小球病

B-cell chronic lymphocytic leukemia, kidney amyloidosis with C3 glomerulopathy

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